Digestive motor

The migrating motor complex (MMC) is a cyclic, recurring motility pattern that occurs in the Stomach and small bowel during fasting. It is interrupted by feeding. This cycle occurs in the upper gastrointestinal (GI) tract, including the Stomach and Small Intestine, during the fasting state. The MMC is known as the housekeeper of the Small Intestines because it clears out food particles to send to the Large Intestine between meals.

An absent or disordered pattern of the MMC is associated with small intestinal bacterial overgrowth (SIBO). Normal GI motility involves a complex, tightly coordinated series of events designed to move material through the GI tract. During periods of fasting, a migrating motor complex (MMC) develops approximately every 90-120 minutes to sweep residual debris through the GI tract. Several studies have demonstrated that abnormalities in the MMC may predispose to the development of SIBO.

The reason for this is most likely because of the increase of food particles in the Small Intestine, which can increase bacteria and lead to overgrowth. Research states that MMC deficiency is seen in 70% of patients who have SIBO. A poorly functioning MMC has also been linked with chronic constipation and irritable bowel syndrome (IBS).

Supporting the function of the MMC may decrease risk of SIBO and IBS. Symptoms such as constipation, gas, and bloating can improve. The easiest way to support this function is to space out your food intake to allow the full MMC cycle to occur between meals and snacks, ideally 3-4 hours. If you focus on well balanced meals, you will find yourself satiated in between meals.